|
T22033 |
ARC 239 dihydrochloride
|
|
Norepinephrine
|
|
ARC 239 dihydrochloride is a selective α2B adrenoceptor antagonist (pKD values are 8.8, 6.7 and 6.4 at α2B, α2A, and α2D receptors respectively). |
|
T12597 |
5-HT2 antagonist 1
|
|
5-HT Receptor
|
|
5-HT2 antagonist 1 is a potent 5-HT2 receptor antagonist, has weak α1 adrenoceptor blocking activity. |
|
T26923 |
Bunazosin Hydrochloride
|
E 1015,E643,E-1015,E-643,E 643 |
Adrenergic Receptor
|
|
Bunazosin Hydrochloride (E 1015) is an alpha(1)-adrenoceptor antagonist used as a systemic antihypertensive and an ocular hypotensive drug. |
|
T30846 |
CGP-20712
|
UNII-SIO2UEZ19H,CGP 20712 |
Adrenergic Receptor
|
|
CGP-20712 is a selective β 1-adrenoceptor antagonist with an IC50 of 0.7 nM. |
|
T11726 |
JP1302 dihydrochloride
|
|
Adrenergic Receptor
|
|
JP1302 dihydrochloride is a selective, high affinity antagonist of the alpha2C-adrenoceptor (α2C-adrenoceptor), with a Ki (binding affinity) value of 28 nM and a Kb value (antagonist activity) of 16 nM. |
|
T28267 |
ORM-10921
|
ORM10921,ORM 10921 |
Adrenergic Receptor
|
|
ORM-10921 is an α2C-adrenoceptor antagonist that has shown antipsychotic and antidepressant activity in animal studies. |
|
T35326 |
Labetalone hydrochloride
|
Labetalone hydrochloride,Benzoic amide |
Others
|
|
Labetalone hydrochloride (Benzoic amide) is an impurity of Labetalol. Labetalol is an orally active adrenoceptor blocking drug, Labetalol is a competitive antagonist at both alpha- and beta-adrenoceptor sites |
|
T30027 |
Amosulalol
|
|
Adrenergic Receptor
|
|
Amosulalol is a combined alpha and beta adrenoceptor antagonist. |
|
T11286 |
Fiduxosin
|
A 185980.1,ABT 980 |
Adrenergic Receptor
|
|
|
|
T11015 |
Midaglizole hydrochloride
|
(±)-DG5128,(±)-DG5128 hydrochloride,DG5128 hydrochloride,DG5128 |
Adrenergic Receptor
|
|
Midaglizole hydrochloride ((±)-DG5128) (DG5128) is a preferred α2-adrenoceptor antagonist. Midazolazole hydrochloride (DG5128) has an affinity for α2-adrenoceptor (pKi = 6.28) 7.4 times higher than that of α1-adrenocepto... |
|
T61535 |
Neldazosin
|
|
Adrenergic Receptor
|
|
Neldazosin is used as a potent α1-adrenoceptor antagonist. |
|
T28922 |
Taprizosin
|
Taprizosin Mesylate,UK-338003,UK-338,003,UK338003,UK 338003 |
Adrenergic Receptor
|
|
Taprizosin（UK-338003） is a selective and orally active α1-adrenoceptor antagonist for vasodilatation in the treatment of benign prostatic hyperplasia. |
|
T0088 |
Urapidil hydrochloride
|
Urapidil HCl |
5-HT Receptor
,
Adrenergic Receptor
|
|
Urapidil hydrochloride (Urapidil HCl) is 5-HT1A receptor agonist and an α1-adrenoceptor antagonist. |
|
T9220 |
Naftopidil hydrochloride
|
1-[4-(2-methoxyphenyl)piperazin-1-yl]-3-,KT-611 hydrochloride,BM-15275 hydrochloride |
Adrenergic Receptor
|
|
Naftopidil hydrochloride (BM-15275 hydrochloride) is a selective alpha1-adrenoceptor antagonist with Ki of 3.7 nM, 20 nM and 1.2 nM for the cloned human α1a-adrenoceptor, α1b-adrenoceptor and α1d-adrenoceptor, respective... |
|
T20898 |
(R)-Propranolol hydrochloride
|
Dexpropranolol hydrochloride,(R)-(+)-Propranolol |
Adrenergic Receptor
|
|
(R)-Propranolol hydrochloride (Dexpropranolol hydrochloride) is the less active enantiomer of the anti-adrenoceptor (β-adrenoceptor) antagonist propranolol. Propranolol is a nonselective β-adrenergic receptor (βAR) antag... |
|
T16431 |
Pamatolol
|
|
Adrenergic Receptor
|
|
|
|
T7079 |
Batefenterol
|
GSK961081,TD-5959 |
Adrenergic Receptor
,
AChR
|
|
Batefenterol (TD-5959) (GSK961081, TD-5959) is a muscarinic receptor antagonist and β2-adrenoceptor agonist. It displays high affinity for hM2, hM3 muscarinic and hβ2-adrenoceptor (Ki:1.4/1.3/3.7 nM). |
|
T9762 |
Upidosin
|
SB-216469,SB 216469,Rec 15-2739,Recordati 15/2739 |
Adrenergic Receptor
|
|
Upidosin (SB-216469) is a potential uroselective α1-adrenoceptor antagonist, α1a subtype Ki=0.34 nM, α1b subtype Ki=3.9 nM, α1d subtype Ki=1.5 nM, α2-adrenoceptor Ki=33.3 nM. |
|
T16798 |
RS 17053 hydrochloride
|
RS-17053 |
Others
,
Adrenergic Receptor
|
|
RS 17053 hydrochloride is a potent and selective antagonist of α1A adrenoceptor. RS 17053 hydrochloride exhibits a pKi value of 9.1 in native cell membrane and a pA2 value of 9.8 in functional assays. |
|
T12643 |
(R)-Terazosin
|
|
Adrenergic Receptor
|
|
(R)-Terazosin is an active R-enantiomer of Terazosin. (R)-Terazosin is a potent antagonist of α1-adrenoceptor (α1a, α1b and α1d-adrenoceptor with Ki values of 6.51 nM, 1.01 nM and 1.97 nM, respectively). |
|
T5028 |
Landiolol hydrochloride
|
ONO-1101 hydrochloride |
Adrenergic Receptor
|
|
Landiolol hydrochloride (ONO-1101 hydrochloride) is an ultra-short-acting β1 selective adrenoceptor antagonist. |
|
T4526 |
Piperoxan hydrochloride
|
dl-Piperoxan hydrochloride,Benodaine hydrochloride |
Adrenergic Receptor
|
|
Piperoxan hydrochloride (Benodaine hydrochloride) is an α2 adrenoceptor antagonist. Piperoxan (benodaine) is a drug which was the very first antihistamine to be discovered. |
|
T0165 |
Urapidil
|
Mediatensyl,Ebrantil,Eupressyl |
5-HT Receptor
,
Adrenergic Receptor
|
|
Urapidil (Ebrantil), a sympatholytic antihypertensive drug, acts as a 5-HT1A receptor agonist and as an α1-adrenoceptor antagonist. |
|
T21640 |
Talinolol
|
|
Adrenergic Receptor
|
|
(±)-Talinolol is a selective β1 adrenoceptor antagonist well known for its cardioprotective and antihypertensive activity. |
|
T15688 |
L-771688
|
SNAP 6383 |
Adrenergic Receptor
|
|
L-771688 (SNAP 6383) is a novel potent and selective α1A-adrenoceptor antagonist with a Ki value of 0.43±0.02 nM.L-771688 KE is used for the treatment of benign prostatic hyperplasia. |
|
T6701 |
Terazosin hydrochloride dihydrate
|
Flotrin dihydrate,Terazosin HCl Dihydrate,Dysalfa dihydrate,Heitrin dihydrate |
Adrenergic Receptor
|
|
Terazosin hydrochloride dihydrate (Heitrin dihydrate) is a selective α1-adrenoceptor antagonist, used for treatment of symptoms of an enlarged prostate (BPH). |
|
T8143 |
Bevantolol hydrochloride
|
NC-1400 hydrochloride |
Calcium Channel
,
Adrenergic Receptor
|
|
Bevantolol hydrochloride (NC-1400 hydrochloride) is a β1-adrenoceptor antagonist that treatment angina pectoris and hypertension. |
|
T62893 |
SM-2470
|
|
Adrenergic Receptor
|
|
SM-2470 is an α1-adrenoceptor antagonist with antihypertensive activity that decreases anterior ganglionic adrenal nerve activity and aortic descending nerve activity.SM-2470 has hypocholesterolemic activity and inhibits... |
|
T77565 |
Fluparoxan hydrochloride
|
|
Adrenergic Receptor
|
|
Fluparoxan hydrochloride is a highly selective and potent α2-adrenoceptor antagonist for the prevention, amelioration or treatment of neurodevelopmental disorders and neurodegenerative diseases. |
|
T23232 |
Remoxipride hydrochloride
|
Remoxipride Hydrochloride Anhydrous,Roxiam,(S)-Remoxipride Hydrochloride |
Dopamine Receptor
|
|
Remoxipride hydrochloride (Roxiam) is a selective antagonist of D2 receptor with IC50s of 1.57 μM, ＞100 μM and 42 μM for D2 receptor, D1 receptor and α1-adrenoceptor. |
|
T7728 |
ACEPROMAZINE MALEATE
|
|
Dopamine Receptor
|
|
ACEPROMAZINE MALEATE is a dopamine receptor antagonist |
|
T25828 |
Monatepil maleate
|
AJ2615 maleate,AJ-2615 maleate,AJ 2615 maleate |
Calcium Channel
,
Adrenergic Receptor
,
Acyltransferase
|
|
Monatepil maleate (AJ-2615 maleate) is an orally active Ca2+-channel and α1-adrenoceptor antagonist and non-competitive heparanoyl-coenzyme A:cholesterol acyltransferase (ACAT) inhibitor with antihypertensive activity.Mo... |
|
T14490 |
Talipexole dihydrochloride
|
Domnin,B-HT 920 dihydrochloride |
Dopamine Receptor
,
5-HT Receptor
,
Adrenergic Receptor
|
|
Talipexole dihydrochloride (Domnin) is a dopamine D2 receptor agonist, α2-adrenoceptor agonist, and 5-HT3 receptor antagonist in both rat cortical and intestinal membrane fractions with Ki values of 0.35 μM and 0.22 μM, ... |
|
T0115 |
Idazoxan hydrochloride
|
RX 781094 |
Adrenergic Receptor
,
Imidazoline Receptor
|
|
Idazoxan hydrochloride (RX 781094) is a benzodioxane-linked imidazole. It has alpha-2 adrenoceptor antagonist activity. |
|
T22882 |
JP1302
|
|
Adrenergic Receptor
|
|
JP1302 is a selective α2C adrenoceptor antagonist with a Kb value of 16 nM and a Ki of 28 nM for human α2C receptors.JP1302 has antidepressant activity, disrupts the FACT complex and degrades histone H1.JP1302 has been u... |
|
T8580 |
Bupranolol
|
|
Adrenergic Receptor
|
|
Bupranolol is an antagonist of β2-adrenergic receptor and has been used for angina pectoris, hypertension, glaucoma, cardiac arrhythmia and as an antithrombotic. |
|
T6600 |
Naftopidil dihydrochloride
|
KT-611,KT-611 2HCl,Naftopidil DiHCl |
5-HT Receptor
,
Adrenergic Receptor
|
|
Naftopidil dihydrochloride (KT-611 2HCl) is a selective 5-HT1A and α1-adrenergic receptor antagonist with IC50 of 0.1 μM and 0.2 μM, respectively. |
|
T68138 |
Saterinone
|
|
Adrenergic Receptor
,
PDE
|
|
Saterinone is a potent and selective phosphodiesterase III inhibitor and a potent antagonist of the vascular α-1-adrenoceptor. Saterinone has vasodilatory properties and can be used in the acute treatment of chronic hear... |
|
T0696 |
Naftopidil
|
KT-611,BM-15275 |
Adrenergic Receptor
|
|
Naftopidil (KT-611) (INN, marketed under the brand name Flivas), an antihypertensive medicine, is used as a selective α1-adrenergic receptor antagonist or α-blocker. |
|
T6765 |
Atipamezole hydrochloride
|
MPV-1248 hydrochloride,Antisedan |
Adrenergic Receptor
|
|
Atipamezole is a synthetic α2 adrenergic receptor antagonist. It has also been researched in humans as a potential anti-Parkinsonian drug. Atipamezole hydrochloride (MPV-1248 hydrochloride) is hydrochloride form of atipa... |
|
T6766 |
Atipamezole
|
Antisedan,MPV 1248 |
Adrenergic Receptor
|
|
Atipamezole (Antisedan) is a synthetic α2 adrenergic receptor antagonist. It has also been researched in humans as a potential anti-Parkinsonian drug. |
|
T1158 |
Phenoxybenzamine hydrochloride
|
NCI-c01661,NSC 37448,Phenoxybenzamine HCl |
CaMK
,
Adrenergic Receptor
|
|
Phenoxybenzamine hydrochloride (NCI-c01661) is the hydrochloride salt form of phenoxybenzamine, a synthetic, dibenzamine alpha-adrenergic antagonist with antihypertensive and vasodilatory properties. Phenoxybenzamine non... |
|
T23374 |
SNAP 5089
|
|
Others
|
|
α1A-adrenoceptor antagonist |
|
T22699 |
Cyanopindolol hemifumarate
|
|
Others
|
|
5-HT1A/1B antagonist and β-adrenoceptor antagonist |
|
T24012 |
Domesticine, (-)-
|
L-Domesticine |
|
|
Domesticine, (-)- is an antagonist of alpha-1D-adrenoceptor. |
|
T23366 |
SKF 86466 hydrochloride
|
|
Others
|
|
SKF 86466 hydrochloride is an α2-adrenoceptor antagonist. |
|
T26134 |
RS 15385-197
|
RS-15385-197,RS15385-197 |
|
|
RS 15385-197 is a selective alpha 2-adrenoceptor antagonist. |
|
T22861 |
Imiloxan hydrochloride
|
|
Others
|
|
Imiloxan hydrochloride is an α2-adrenoceptor antagonist. |
|
T23836 |
Bufetolol
|
|
|
|
Bufetolol is an antagonist of beta-adrenoceptor. |
|
T22500 |
2-PMDQ
|
|
Others
|
|
2-PMDQ is an α1-adrenoceptor antagonist. |
